Impact of memory footprint on performance

Impact of memory footprint on performance

We have a .Net (VS 2012) 64 bit application, running on Windows Server
2012, which loads lots of data in memory to work with it for next 24 - 48
hours. As per our design we prefer to load the data upfront by connecting
to the Data source. Net memory footprint of the process goes up to 7-8 GB,
which is because we replicate the data for 4 independent threads, which
represent the parallel clients, so it like 2 GB of Data per client.
Hardware that we are using is having 128 GB of RAM, 4 CPU (24 Core) processor
I was wondering that does the memory footprint will have an impact on the
net performance of the process, like speed of execution, processor
utilization etc
Even when we have such a good RAM and the net usage never exceed 60%, will
there still be swapping of process pages to HD, thus making it slower,
when it is continuously used for 48 hours. Is there some server settings
or .Net c# code API, that will help us taking care of performance issues
occurring due to memory footprint. We can explicitly tell the system that
our process needs lots of memory